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Archive for the ‘news’ Category

FOX 7 Care Force: Vandry Hope Foundation

Posted on: August 11th, 2017 |

Thanks to their commitment though, they are making a big difference for the veterans they see.

 “So why is an Army brat, a Brazilian jiu jitsu instructor and his Navy veteran spouse helping veterans struggling with pain?  The one word answer is – honor.”

“If you can make a difference with one person that’s worth it,” says William Vandry.

So what exactly does the Vandry Foundation do?

“Vets have come to us with pain, stress, anxiety, can’t sleep…they’re tired of opiods..they want some hope.  So we give them knowledge about alternatives that we know about and we’ve tried.  We are not prescribing, we are not doctors but we say what we’ve found and the options, and we’ve had some great success with that.”

The Vandry Hope Foundation was created two years ago and operates out of a studio in North Austin.

To learn more about the Vandry Hope Foundation you can click here. 

 


St. Jude’s Miracle oilTM July 9, 2016 Got Pain?, Got sight? and Got canine pain? expo

Posted on: July 1st, 2016 |

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Miracle oil Co-inventor speaks on joints, inflammation and nutrition at Got pain? expo

Posted on: September 21st, 2015 |

September 19, 2015

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Got pain? clinic thumbs up approval

St Jude’s Miracle Oil® Co-inventor Chandra Vandry was lead speaker at the second Got Pain? clinic on nutrition, joints, inflammation, and also covered a variety of topics such as insomnia, migraines, foods, minerals, and many other points on health issues in today’s society.  November 2014 the first Got Pain? clinic was held in Dallas/Ft. Worth.  On her powerpoint, statistics on diet, and every day issues were referenced via PubMed, NCBI and other medical journals.  Questions such as insomnia and migraines were discussed, and many testimonies of the St Jude’s Miracle Oil® product were mentioned by the audience.  The Vandry’s have been asked to speak again in the DFW area later this year.

Dietary changes discussed.

gotpain2

Supportive audience for Got Pain? clinic!


Got pain? September 19 Austin Clinic regarding nutrition, joints, inflammation and Miracle oil!

Posted on: September 9th, 2015 |

Dallas Ft. Worth hosted the first Got Pain? clinic regarding nutrition, joints, inflammation, and the St. Jude’s Miracle oilTM product last year.  This year September 19 speakers Chandra and William Vandry will cover these topics for educational purposes.  Lead speaker Chandra Vandry will discuss new research and answer questions.

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St. Jude’s Miracle oilTM at Martial arts Health Expo DFW

Posted on: November 10th, 2014 |

November 9, 2014

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Photo: St. Jude’s Miracle oilTM Co-inventors and Martial artists William and Chandra Vandry

The Martial arts and Health expo hosted by Professor Marcos Santos in Dallas Ft Worth had co speakers William and Chandra Vandry addressing medical information, and their product, Miracle oil.  Lead Speaker Chandra Vandry, and R.N. in neurology and allergy, discussed JAMA, NCBI and PubMed references to the plague of Chronic pain in the USA.  Chronic pain effects more people in the USA than Diabetes, Cancer or heart disease combined.  Pain statistics show:

Chronic pain 116 million (Institute of medicine of national academies)

Diabetes 25.8 million americans (American Diabetes Association)

Heart disease 16.3 million americans (American Heart Association)

Cancer 11.9 million americans (American cancer society)

Vandry also discussed the FDA’s warning on NSAIDS, and the overuse of them.  As she finished with a question and answer section, many in the audience discussed their own chronic pain, migraines, arthritis and other pain related conditions.

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Vandry’s addressing questions.  Marcos Santos to the right.

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student Matt Brazille and Expo host Professor Marcos Santos of RCJ Machado academy Ft Worth.

 


Jiu-jitsu Master Carlos Machado promotes St. Jude’s Miracle oilTM on radio interview

Posted on: October 19th, 2014 |

 

carlosmsjmo

Photo: Master Carlos Machado holding bottle of St. Jude’s Miracle oilTM and co-inventor and student William Vandry

On October 14, 2014 world re-known BJJ Master Carlos Machado was interviewed by Carlos Kremer on his radio show.  Machado is of the famous Machado brothers from Brazil, and is one of the leaders of Brazilian Jiu-jitsu worldwide.  Machado is the nephew of the founder of Brazilian Jiu-jitsu, Grandmaster Carlos Gracie.  In the interview, Machado discusses philosophy, history, his upcoming Machado brothers camp, which will be on the October 24-26 weekend in Dallas, Texas.  Machado, who is also a consumer and promoter of St. Jude’s Miracle oilTM, discusses the product in his interview with Carlos Kremer.  The link below has the full interview:

http://wsradio.com/category/entertainment-radio/kick-ass-radio/

On the third segment at 3:04 Master Carlos Machado discusses the effects of St. Jude’s Miracle oilTM, and gives a nice plug:

CM: I, before I came here I just wanted to mention I talked to one of my black belts, we are very health oriented.  I have a Black belt called William Vandry, he’s among one of my first black belts and he is a great story in itself, an amazing man that has overcome incredible obstacles.  He created an oil called the St. Jude’s Miracle oilTM, and for us who do Jiu-jitsu that are always complaining about our joints, or people take cortisone shots, anti inflammatory things can be harmful to your health.  This oil, if you go to their facebook page, just type St. Jude’s Miracle Oil.

CK: Aha

CM: Youre gonna find information, and I kid you not, when I send you my book, I am also gonna send a sample of that oil.

CK: Ok

CM: And your gonna tell me once you put that thing on any joint that aches, what is gonna happen afterwards.

CK:  You know that I could use that, that’s incredible because I ache all over..


Health and Martial arts Dallas Ft. Worth Expo featuring St. Jude’s Miracle oilTM product

Posted on: October 12th, 2014 |

 

Expo Poster3 (2)
Disclaimer

Information within this site is for educational purposes only. The U.S. Food & Drug Administration has not evaluated statements about the product efficacy. These products are not intended to diagnose, treat, cure, or prevent any disease.

Co-inventors of St. Jude’s Miracle oilTM will be discussing the effects of their Miracle Oil product.  Discussion will be on nutrition, inflammation, degeneration of joints in society.   A research team led by Carnegie Mellon University’s Sheldon Cohen has found that chronic psychological stress is associated with the body losing its ability to regulate the inflammatory response. Published in the Proceedings of the National Academy of Sciences, the research shows for the first time that the effects of psychological stress on the body’s ability to regulate inflammation can promote the development and progression of disease1.

Journal Reference:

  1. Sheldon Cohen,    Denise Janicki-Deverts,    William J. Doyle,    Gregory E. Miller,    Ellen Frank,    Bruce S. Rabin,    and Ronald B. Turner. Chronic stress, glucocorticoid receptor resistance, inflammation, and disease risk. PNAS, April 2, 2012 DOI: 10.1073/pnas.1118355109

The clinic will discuss degeneration of disks, and medical studies with Collagen II.  Researchers at Harvard’s Beth Israel Hospital in Boston have studied Collagen II extensively in patients with rheumatoid arthritis. In one study of 60 patients with active rheumatoid arthritis, a decrease in the number of swollen and tender joints was found in subjects who supplemented with Collagen II for 3 months, but not in placebo recipients.2

2. Trentham DE, Dynesius-Trentham RA, Orav EJ, et al. Effects of oral administration of type II collagen on rheumatoid arthritis. Science. 1993 Sep 24;261(5129):1727-30

The main topic will be on the Miracle oil product, the references to studies on essential oils from medical journals.

 


Essential oils vs. viruses, MDR bacteria, MRSA, Staph, E coli, Pseudomonas, Candida

Posted on: October 9th, 2014 |

3x5_sjmo

DISCLAIMER

Information within this site is for educational purposes only. The U.S. Food & Drug Administration has not evaluated statements about the product efficacy. These products are not intended to diagnose, treat, cure, or prevent any disease.

Research on essential oils is limited, and more funding would be appropriate.  Below are medical journals from NCBI and PubMed medical journals specifically correlating essential oils effect on above viruses, strains, etc.  Our research is comparing the oils specifically from St. Jude’s Miracle oilTM (peppermint, eucalyptus, lavender, geranium, clary sage, clove bud, myrrh, and frankincense and wintergreen) and effect on viruses, MDR, MSSA, MRSA,  bacteria, staph and others.

1. Peppermint effect on Influenza, viruses

2. Eucalyptus antibacterial effect against multidrug-resistant (MDR) bacteria

3. Lavender effect against MSSA and MRSA

4. Patchouli, tea tree, geranium, lavender essential oils and Citricidal (grapefruit seed extract) anti-bacterial activity

5. Thyme and Eucalyptus effect against MRSA

6. Lavender against antibiotic-restistant bacteria

7. Lavender oil, petigrain oil, clary sage oil, ylang ylang oil and jasmine combination against Staph

8. Antimicrobial activity of geranium oil against clinical strains of Staphylococcus aureus

9. Essential oils (including Eucalyptus, Lavender, Clove Bud, Peppermint)  effective antiseptic topical treatment for MRSA and antimycotic-resistant Candida species

10. Black pepper, cananga, and myrrh oils have potential against  Staphylococcus aureus

11. Myrrh antibacterial, antifungal activity against pathogenic strains E coli, Staph, Pseudomonas and Candida

12. Frankincense (Boswellia serrata) effective against Staphylococcus

13. Wintergreen acts as an anti-inflammatory  and antimicrobial agent

1. Peppermint effect on Influenza, viruses

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957173/

Mentha piperita, family Labiatae, is a herbaceous rhizomatous perennial plant widely used in Ayurveda [78]. It contains about 1.2%–1.5% essential oil. The volatile oil, also known as menthae piperitae aetheroleum, contains 30–70% free menthol, menthol esters and more than 40 other compounds. The principal components of the oil are menthol (29%), menthone (20%–30%), and menthyl acetate (3%–10%). Pharmaceutical grade oil, produced by distilling the fresh aerial parts of the plant at the beginning of the flowering cycle, is standardized to contain no less than 44% menthol, 15%–30% menthone, and 5% esters, in addition to various terpenoids. Other compounds found in it are flavonoids (12%), polymerized polyphenols (19%), carotenes, tocopherols, betaine, and choline [79]. The antimicrobial and antiviral activity of menthol has been reported. Mentha piperita has significant antiviral activity [80]. Menthol is virucidal against influenza, herpes, and other viruses in vitro. Aqueous extracts of peppermint leaves exhibited antiviral activity against Influenza A, Newcastle disease virus, Herpes simplex virus, and Vaccinia virus in egg and cell-culture systems [81]. The oil contains terpenoids such as α-pinene or β-pinene, α-phellandren, and also ester-connected with menthol or free acetic acid and isovaleric acid, which are mainly responsible for the antimicrobial activity of the herb [82].

78. Peirce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New   York, NY, USA: William Morrow; 1999.

79. MurrayMT. The Healing Power of Herbs: The Enlightened Person’s Guide to the Wonders of Medicinal Plants. Vol. 25. Rocklin, Calif, USA: Prima; 1995.

80. Herrmann EC, Jr., Kucera LS. Antiviral substances in plants of the mint family (labiatae). 3. Peppermint (Mentha piperita) and other mint plants. Proceedings of the Society for Experimental Biology and Medicine. 1967;124(3):874–878. [PubMed]

81. Herrmann EC, Jr., Kucera LS. Antiviral substances in plants of the mint family (labiatae). 3. Peppermint (Mentha piperita) and other mint plants. Proceedings of the Society for Experimental Biology and Medicine. 1967;124(3):874–878. [PubMed]

82. Valsaraj R, Pushpangadan P, Smitt UW, Adsersen A, Nyman U. Antimicrobial screening of selected medicinal plants from India. Journal of Ethnopharmacology. 1997;58(2):75–83. [PubMed]

2. Eucalyptus antibacterial effect against multidrug-resistant (MDR) bacteria

http://www.ncbi.nlm.nih.gov/pubmed/21591991

Pharm Biol. 2011 Sep;49(9):893-9. doi: 10.3109/13880209.2011.553625. Epub 2011 May 19.

Antibacterial activity of essential oils from Eucalyptus and of selected components against multidrug-resistant bacterial pathogens.

Mulyaningsih S1, Sporer F, Reichling J, Wink M.

Author information

1Institute of Pharmacy and Molecular Biotechnology, HeidelbergUniversity, Im Neuenheimer Feld, Heidelberg, Germany.

Abstract

CONTEXT: Eucalyptus globulus Labill (Myrtaceae) is the principal source of eucalyptus oil in the world and has been used as an antiseptic and for relieving symptoms of cough, cold, sore throat, and other infections. The oil, well known as ‘eucalyptus oil’ commercially, has been produced from the leaves. Biological properties of the essential oil of fruits from E. globulus have not been investigated much.

OBJECTIVE: The present study was performed to examine the antimicrobial activity of the fruit oil of E. globulus (EGF) and the leaf oils of E. globulus (EGL), E. radiata Sieber ex DC (ERL) and E. citriodora Hook (ECL) against multidrug-resistant (MDR) bacteria. Furthermore, this study was attempted to characterize the oils as well as to establish a relationship between the chemical composition and the corresponding antimicrobial properties.

MATERIALS AND METHODS: The chemical composition of the oils was analyzed by GLC-MS. The oils and isolated major components of the oils were tested against MDR bacteria using the broth microdilution method.

RESULTS: EGF exerted the most pronounced activity against methicillin-resistant Staphylococcus aureus (MIC ~ 250 µg/ml). EGF mainly consisted of aromadendrene (31.17%), whereas ECL had citronellal (90.07%) and citronellol (4.32%) as the major compounds. 1,8-cineole was most abundant in EGL (86.51%) and ERL (82.66%).

DISCUSSION AND CONCLUSION: The activity of the oils can be ranked as EGF > ECL > ERL ~ EGL. However, all the oils and the components were hardly active against MDR Gram-negative bacteria. Aromadendrene was found to be the most active, followed by citronellol, citronellal and 1,8-cineole

3. Lavender effect against MSSA and MRSA

http://www.ncbi.nlm.nih.gov/pubmed/19249919

J Altern Complement Med. 2009 Mar;15(3):275-9. doi: 10.1089/acm.2008.0268.

The antimicrobial activity of high-necrodane and other lavender oils on methicillin-sensitive and -resistant Staphylococcus aureus (MSSA and MRSA).

Roller S1, Ernest N, Buckle J.

Author information

1Faculty of Health and Human Sciences, ThamesValleyUniversity, Brentford, UK. [email protected]

Abstract

OBJECTIVE: The objective of this study was to compare the antimicrobial efficacy of several lavender oils, used singly and in combination, on methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA).

METHODS: Four chemically characterized essential oils from Lavandula angustifolia, L. latifolia, L. stoechas, and a necrodane-rich L. luisieri were assessed for their antibacterial activity using the disc diffusion method.

RESULTS: All four lavender oils inhibited growth of both MSSA and MRSA by direct contact but not in the vapor phase. Inhibition zones ranged from 8 to 30 mm in diameter at oil doses ranging from 1 to 20 microL, respectively, demonstrating a dose response. At any single dose, the extent of inhibition was very similar irrespective of the chemical composition of the oils or the strain of S. aureus used. Several binary combinations of the oils were tested, and the results showed that the necrodane-rich L. luisieri oil interacted synergistically with L. stoechas (high in 1,8-cineole, fenchone, and camphor) and L. langustifolia (rich in linalool and linalyl acetate) to produce larger inhibition zones than those produced using each oil individually.

CONCLUSIONS: The results suggest that combinations of lavender oils should be investigated further for possible use in antibacterial products.

Burns. 2004 Dec;30(8):772-7.

4. Patchouli, tea tree, geranium, lavender essential oils and Citricidal (grapefruit seed extract) anti-bacterial activity

The effect of essential oils on methicillin-resistant Staphylococcus aureus using a dressing model.

Edwards-Jones V1, Buck R, Shawcross SG, Dawson MM, Dunn K.

Author information

1Department of Biological Sciences, the ManchesterMetropolitanUniversity, Chester Street, Manchester, M15GD, UK. [email protected]

Abstract

Patchouli, tea tree, geranium, lavender essential oils and Citricidal (grapefruit seed extract) were used singly and in combination to assess their anti-bacterial activity against three strains of Staphylococcus aureus: Oxford S. aureus NCTC 6571 (Oxford strain), Epidemic methicillin-resistant S. aureus (EMRSA 15) and MRSA (untypable). The individual essential oils, extracts and combinations were impregnated into filter paper discs and placed on the surface of agar plates, pre-seeded with the appropriate strain of Staphylococcus. The effects of the vapours of the oils and oil combinations were also assessed using impregnated filter paper discs that were placed on the underside of the Petri dish lid at a distance of 8mm from the bacteria. The most inhibitory combinations of oils for each strain were used in a dressing model constructed using a four layers of dressings: the primary layer consisted of either Jelonet or TelfaClear with or without Flamazine; the second was a layer of gauze, the third a layer of Gamgee and the final layer was Crepe bandage. The oil combinations were placed in either the gauze or the Gamgee layer. This four-layered dressing was placed over the seeded agar plate, incubated for 24h at 37 degrees C and the zones of inhibition measured. All experiments were repeated on three separate occasions. No anti-bacterial effects were observed when Flamazine was smeared on the gauze in the dressing model. When Telfaclear was used as the primary layer in the dressing model compared to Jelonet, greater zones of inhibition were observed. A combination of Citricidal and geranium oil showed the greatest-anti-bacterial effects against MRSA, whilst a combination of geranium and tea tree oil was most active against the methicillin-sensitive S. aureus (Oxford strain). This study demonstrates the potential of essential oils and essential oil vapors as antibacterial agents and for use in the treatment of MRSA infection.

5. Thyme and Eucalyptus effect against MRSA

2010 Feb;17(2):142-5. doi: 10.1016/j.phymed.2009.05.007. Epub 2009 Jul 2.

Antibacterial effect of essential oils from two medicinal plants against Methicillin-resistant Staphylococcus aureus (MRSA).

Tohidpour A1, Sattari M, Omidbaigi R, Yadegar A, Nazemi J.

Author information

1Department of Bacteriology, School of Medical Sciences, TarbiatModaresUniversity, P.O. Box: 14115-158, Tehran, Iran.

Abstract

Antimicrobial properties of plants essential oils (EOs) have been investigated through several observations and clinical studies which purpose them as potential tools to overcome the microbial drug resistance problem. The aim of this research is to study the antibacterial effect of two traditional plants essential oils, Thymus vulgaris and Eucalyptus globulus against clinical isolates of Methicillin resistant Staphylococcus aureus (MRSA) and other standard bacterial strains through disk diffusion and agar dilution methods. Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) analysis examined the chemical composition of the oils. Results revealed both of oils to possess degrees of antibacterial activity against Gram (+) and Gram (-) bacteria. T. vulgaris EO showed better inhibitory effects than E. globulus essential oil. GC analysis of T. vulgaris resulted in thymol as the oil major compound whereas GC/MS assay exhibited eucalyptol as the most abundant constitute of E. globulus EO. These results support previous studies on these oils and suggest an additional option to treat MRSA infections. Clinical and further analytical trials of these data are necessary to confirm the obtained outcomes.

Copyright 2009. Published by Elsevier GmbH.

6. Lavender against antibiotic-restistant bacteria

Nat Prod Res. 2014 Aug 30:1-4.

Chemical composition and antibacterial activity of Lavandula coronopifolia essential oil against antibiotic-resistant bacteria.

Ait Said L1, Zahlane K, Ghalbane I, El Messoussi S, Romane A, Cavaleiro C, Salgueiro L.

Author information

1a Laboratory of Molecular and Ecophysiology Modeling, Faculty of Sciences-Semlalia , CadiAyyadUniversity , Marrakech , Morocco.

Abstract

The aim of this study was to analyse the composition of the essential oil (EO) of Lavandula coronopifolia from Morocco and to evaluate its in vitro antibacterial activity against antibiotic-resistant bacteria isolated from clinicalinfections. The antimicrobial activity was assessed by a broth micro-well dilution method using multiresistant clinical isolates of 11 pathogenic bacteria: Klebsiella pneumoniae subsp. pneumoniae, Klebsiella ornithinolytica, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Providencia rettgeri, Citrobacter freundii, Hafnia alvei, Salmonella spp., Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus. The main compounds of the oil were carvacrol (48.9%), E-caryophyllene (10.8%) and caryophyllene oxide (7.7%). The oil showed activity against all tested strains with minimal inhibitory concentration (MIC) values ranging between 1% and 4%. For most of the strains, the MIC value was equivalent to the minimal bactericidal concentration value, indicating a clear bactericidal effect of L. coronopifolia EO.

7. lavender oil, petigrain oil, clary sage oil, ylang ylang oil and jasmine combination against Staph

See comment in PubMed Commons below

Nat Prod Commun. 2012 Oct;7(10):1401-4.

Antimicrobial activity of blended essential oil preparation.

Tadtong S1, Suppawat S, Tintawee A, Saramas P, Jareonvong S, Hongratanaworakit T.

Author information

1Faculty of Pharmacy, Srinakharinwirot University, 63 Moo 7, Rangsit-Nakhon-nayok Rd., Ongkharak, Nakhon-nayok, 26120, Thailand. [email protected]

Abstract

Antimicrobial activities of two blended essential oil preparations comprising lavender oil, petigrain oil, clary sage oil, ylang ylang oil and jasmine oil were evaluated against various pathogenic microorganisms. Both preparations showed antimicrobial activity in the agar disc diffusion assay against the Gram-positive bacteria, Staphylococcus aureus ATCC6538 and S. epidermidis isolated strain, the fungus, Candida albicans ATCC10231, and the Gram-negative bacterium, Escherichia coli ATCC25922, but showed no activity against Pseudomonas aeruginosa ATCC9027. The minimum inhibitory concentration (MIC) of these preparations was evaluated. By the broth microdilution assay, preparation 1, comprising lavender oil, clary sage oil, and ylang ylang oil (volume ratio 3:4:3), exhibited stronger antimicrobial activity than preparation 2, which was composed of petigrain oil, clary sage oil, and jasmine oil (volume ratio 3:4:3). Moreover, the sum of the fractional inhibitory concentrations (Sigma fic) of preparation 1 expressed a synergistic antimicrobial effect against the tested microorganisms (Sigma fic<l). The blended essential oil preparations, characterized for their components by GC/MS, contained linalyl acetate, and linalool as major components. Our experiments showed that the differential antimicrobial effect of either blended oil preparations or single/pure essential oils may be influenced by the amount of linalool and linalyl acetate, and the number of active components in either the blended preparations or single/pure essential oils. In addition, blended oil preparations expressed synergistic antimicrobial effect by the accumulation of active components such as linalool and linalyl acetate and combining active constituents of more than one oil.

8. Antimicrobial activity of geranium oil against clinical strains of Staphylococcus aureus

See comment in PubMed Commons below

Molecules. 2012 Aug 28;17(9):10276-91. doi: 10.3390/molecules170910276.

Antimicrobial activity of geranium oil against clinical strains of Staphylococcus aureus.

Bigos M1, Wasiela M, Kalemba D, Sienkiewicz M.

Author information

1Medical and Sanitary Microbiology Department, Medical University of Lodz, Hallera Sq. 1, Lodz 90-647, Poland. [email protected]

Abstract

The aim of this work was to investigate the antibacterial properties of geranium oil obtained from Pelargonium graveolens Ait. (family Geraniaceae), against one standard S. aureus strain ATCC 433000 and seventy clinical S. aureus strains. The agar dilution method was used for assessment showed that the oil from P. graveolens has strong activity against all of the clinical S. aureus isolates-including multidrug resistant strains, MRSA strains and MLS(B)-positive strains-exhibiting MIC values of 0.25-2.50 μL/mLof bacterial growth inhibition at various concentrations of geranium oil. Susceptibility testing of the clinical strains to antibiotics was carried out using the disk-diffusion and E-test methods. The results of our experiment

9. Essential oils (including Eucalyptus, Lavender, Clove Bud, Peppermint)  effective antiseptic topical treatment for MRSA and antimycotic-resistant Candida species

http://www.ncbi.nlm.nih.gov/pubmed/19473851

J Craniomaxillofac Surg. 2009 Oct;37(7):392-7. doi: 10.1016/j.jcms.2009.03.017. Epub 2009 May 26.

The battle against multi-resistant strains: Renaissance of antimicrobial essential oils as a promising force to fight hospital-acquired infections.

Warnke PH1, Becker ST, Podschun R, Sivananthan S, Springer IN, Russo PA, Wiltfang J, Fickenscher H, Sherry E.

Author information

1Department of Oral and Maxillofacial Surgery, University of Kiel, Germany. [email protected]

Abstract

Hospital-acquired infections and antibiotic-resistant bacteria continue to be major health concerns worldwide. Particularly problematic is methicillin-resistant Staphylococcus aureus (MRSA) and its ability to cause severe soft tissue, bone or implant infections. First used by the Australian Aborigines, Tea tree oil and Eucalyptus oil (and several other essential oils) have each demonstrated promising efficacy against several bacteria and have been used clinically against multi-resistant strains. Several common and hospital-acquired bacterial and yeast isolates (6 Staphylococcus strains including MRSA, 4 Streptococcus strains and 3 Candida strains including Candida krusei) were tested for their susceptibility for Eucalyptus, Tea tree, Thyme white, Lavender, Lemon, Lemongrass, Cinnamon, Grapefruit, Clove Bud, Sandalwood, Peppermint, Kunzea and Sage oil with the agar diffusion test. Olive oil, Paraffin oil, Ethanol (70%), Povidone iodine, Chlorhexidine and hydrogen peroxide (H(2)O(2)) served as controls. Large prevailing effective zones of inhibition were observed for Thyme white, Lemon, Lemongrass and Cinnamon oil. The other oils also showed considerable efficacy. Remarkably, almost all tested oils demonstrated efficacy against hospital-acquired isolates and reference strains, whereas Olive and Paraffin oil from the control group produced no inhibition. As proven in vitro, essential oils represent a cheap and effective antiseptic topical treatment option even for antibiotic-resistant strains as MRSA and antimycotic-resistant Candida species.

10. Black pepper, cananga, and myrrh oils have potential against  Staphylococcus aureus

Appl Microbiol Biotechnol. 2014 Jul 16

Anti-biofilm, anti-hemolysis, and anti-virulence activities of black pepper, cananga, myrrh oils, and nerolidol against Staphylococcus aureus.

Lee K1, Lee JH, Kim SI, Cho MH, Lee J.

Author information

1School of Chemical Engineering, YeungnamUniversity, Gyeongsan, 712-749, Republic of Korea.

Abstract

The long-term usage of antibiotics has resulted in the evolution of multidrug-resistant bacteria. Unlike antibiotics, anti-virulence approaches target bacterial virulence without affecting cell viability, which may be less prone to develop drug resistance. Staphylococcus aureus is a major human pathogen that produces diverse virulence factors, such as α-toxin, which is hemolytic. Also, biofilm formation of S. aureus is one of the mechanisms of its drug resistance. In this study, anti-biofilm screening of 83 essential oils showed that black pepper, cananga, and myrrh oils and their common constituent cis-nerolidol at 0.01 % markedly inhibited S. aureus biofilm formation. Furthermore, the three essential oils and cis-nerolidol at below 0.005 % almost abolished the hemolytic activity of S. aureus. Transcriptional analyses showed that black pepper oil down-regulated the expressions of the α-toxin gene (hla), the nuclease genes, and the regulatory genes. In addition, black pepper, cananga, and myrrh oils and cis-nerolidol attenuated S. aureus virulence in the nematode Caenorhabditis elegans. This study is one of the most extensive on anti-virulence screening using diverse essential oils and provides comprehensive data on the subject. This finding implies other beneficial effects of essential oils and suggests that black pepper, cananga, and myrrh oils have potential use as anti-virulence strategies against persistent S. aureus infections.

11. Myrrh antibacterial, antifungal activity against pathogenic strains E coli, Staph, Pseudomonas and Candida

2000 May;66(4):356-8.

Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh.

Dolara P, Corte B, Ghelardini C, Pugliese AM, Cerbai E, Menichetti S, Lo Nostro A.

Abstract

We extracted, purified and characterized 8 sesquiterpene fractions from Commyphora molmol. In particular, we focused our attention on a mixture of furanodiene-6-one and methoxyfuranoguaia-9-ene-8-one, which showed antibacterial and antifungal activity against standard pathogenic strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans, with minimum inhibitory concentrations ranging from 0.18 to 2.8 micrograms/ml. These compounds also had local anaesthetic activity, blocking the inward sodium current of excitable mammalian membranes

12. Frankincense (Boswellia serrata) effective against Staphylococcus

BMC Microbiol. 2011 Mar 16;11:54. doi: 10.1186/1471-2180-11-54.

Antistaphylococcal and biofilm inhibitory activities of acetyl-11-keto-β-boswellic acid from Boswellia serrata.

Raja AF1, Ali F, Khan IA, Shawl AS, Arora DS, Shah BA, Taneja SC.

Author information

1Microbiology Unit, Indian Institute of Integrative Medicine (CSIR), Sanatnagar, Srinagar, 190005, India.

Abstract

BACKGROUND: Boswellic acids are pentacyclic triterpenes, which are produced in plants belonging to the genus Boswellia. Boswellic acids appear in the resin exudates of the plant and it makes up 25-35% of the resin. β-boswellic acid, 11-keto-β-boswellic acid and acetyl-11-keto-β-boswellic acid have been implicated in apoptosis of cancer cells, particularly that of brain tumors and cells affected by leukemia or colon cancer. These molecules are also associated with potent antimicrobial activities. The present study describes the antimicrobial activities of boswellic acid molecules against 112 pathogenic bacterial isolates including ATCC strains. Acetyl-11-keto-β-boswellic acid (AKBA), which exhibited the most potent antibacterial activity, was further evaluated in time kill studies, postantibiotic effect (PAE) and biofilm susceptibility assay. The mechanism of action of AKBA was investigated by propidium iodide uptake, leakage of 260 and 280 nm absorbing material assays.

RESULTS: AKBA was found to be the most active compound showing an MIC range of 2-8 μg/ml against the entire gram positive bacterial pathogens tested. It exhibited concentration dependent killing of Staphylococcus aureus ATCC 29213 up to 8 × MIC and also demonstrated postantibiotic effect (PAE) of 4.8 h at 2 × MIC. Furthermore, AKBA inhibited the formation of biofilms generated by S. aureus and Staphylococcus epidermidis and also reduced the preformed biofilms by these bacteria. Increased uptake of propidium iodide and leakage of 260 and 280 nm absorbing material by AKBA treated cells of S aureus indicating that the antibacterial mode of action of AKBA probably occurred via disruption of microbial membrane structure.

CONCLUSIONS: This study supported the potential use of AKBA in treating S. aureus infections. AKBA can be further exploited to evolve potential lead compounds in the discovery of new anti-Gram-positive and anti-biofilm agents.

13. Wintergreen acts as an anti-inflammatory  and antimicrobial agent

Anti-inflammatory activity of methyl salicylate glycosides isolated from Gaultheria yunnanensis (Franch.) Rehder.Zhang D, Liu R, Sun L, Huang C, Wang C, Zhang DM, Zhang TT, Du GH.  Molecules. 2011 May 9;16(5):3875-84. doi: 10.3390/molecules16053875


Can oils in St. Jude’s Miracle oil repel mosquitoes?

Posted on: July 23rd, 2013 |

My wife posted a comment on the SJMO facebook page regarding mosquitoes.  About a year ago, each time we would take the dogs out, we would get bit.  About a year ago, I rubbed my oil on my neck and leftover oil I rubbed on my arms and one leg.  I took the dogs out, and came back with one leg bitten by mosquitoes!  I was perplexed why it was only one leg, until I came to the conclusion that it was related to the oil.  To research further, I went to PubMed and there it is!  Research shows 38 oils are mosquito repellents!  The top one is Clove oil, which we have in our product. (1)

I wanted to dig in  a little more, and found more pubmed (ncbi) studies that has more discussion on oils with mosquitoes.  Again we find three out of five oils used in this anti repellent clinical are oils we use in our product (geranium, clove, peppermint, the other two used in this trial were cedarwood and thyme) (2).

Mosquito repellent inventions show 1/3 are using essential oils.  In this pubmed article, the main oils used for inventions were: Camphor [Cinnamomum camphora (L.) J. Presl], cinnamon (Cinnamomum zeylanicum Blume), clove [Syzygium aromaticum (L.) Merr. & L.M. Perry], geranium (Pelargonium graveolens LʼHér.), lavender (Lavandula angustifolia Mill.), lemon [Citrus × limon (L.) Osbeck], lemongrass [Cymbopogon citratus (DC.) Stapf] and peppermint (Mentha × piperita L.)  Here again it shows a consistency with the oils in our product for the repellent affect.  Half of the oils used are Clove, Lavender, Peppermint and Geranium(3).

To show a more direct effect on our oils, peppermint essential oil is proved to be efficient larvicide (4).

Eucalyptus, geranium, and lavender together without any other oils in this study are a very effective mosquito repellent(5).

Frankincense(6) and Myrrh(7) are lethal to larvae of mosquitos.   Perhaps a diluted SJMO with water or oil to rub or spray may repel mosquitos!  We would love to do more studies on mosquito bites and our oil.  In the picture section of this website, it does show how the SJMO reduces mosquito bites within a short time.

References:

1. Phytother Res. 2005 Apr;19(4):303-9.

Comparative repellency of 38 essential oils against mosquito bites.

Trongtokit Y, Rongsriyam Y, Komalamisra N, Apiwathnasorn C.

Source

Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. [email protected]

Abstract

The mosquito repellent activity of 38 essential oils from plants at three concentrations was screened against the mosquito Aedes aegypti under laboratory conditions using human subjects. On a volunteer’s forearm, 0.1 mL of oil was applied per 30 cm2 of exposed skin. When the tested oils were applied at a 10% or 50% concentration, none of them prevented mosquito bites for as long as 2 h, but the undiluted oils of Cymbopogon nardus (citronella), Pogostemon cablin (patchuli), Syzygium aromaticum (clove) and Zanthoxylum limonella (Thai name: makaen) were the most effective and provided 2 h of complete repellency. From these initial results, three concentrations (10%, 50% and undiluted) of citronella, patchouli, clove and makaen were selected for repellency tests against Culex quinquefasciatus and Anopheles dirus. As expected, the undiluted oil showed the highest protection in each case. Clove oil gave the longest duration of 100% repellency (2-4 h) against all three species of mosquito

2. J Med Entomol. 1999 Sep;36(5):625-9.

Repellency of essential oils to mosquitoes (Diptera: Culicidae).

Barnard DR.

Source

Center for Medical, Agricultural, and Veterinary Entomology, USDA-ARS, Gainesville, FL 32604, USA.

Abstract

The repellency of different concentrations (5, 10, 25, 50, 75, and 100%) and combinations of 5 essential oils (Bourbon geranium, cedarwood, clove, peppermint, and thyme) to Aedes aegypti (L.) and Anopheles albimanus Wiedemann when applied to human skin was determined in laboratory tests. Cedarwood oil failed to repel mosquitoes and only high concentrations of peppermint oil repelled Ae. aegypti. None of the oils tested prevented mosquito bite when used at the 5 or 10% concentration. Thyme and clove oils were the most effective mosquito repellents and provided 1 1/2 to 3 1/2 h of protection, depending on oil concentration. Clove oil (50%) combined with geranium oil (50%) or with thyme oil (50%) prevented biting by An. albimanus for 1 1/4 to 2 1/2 h. The potential for using essential oils as topical mosquito repellents may be limited by user acceptability; clove, thyme, and peppermint oils can be irritating to the skin, whereas both human subjects in this study judged the odor of clove and thyme oils unacceptable at concentrations > or = 25%.

3. Planta Med. 2011 Apr;77(6):598-617. doi: 10.1055/s-0030-1270723. Epub  2011 Feb 15.

Patent literature on mosquito repellent inventions which contain plant essential oils–a review.

Pohlit AM, Lopes NP, Gama RA, Tadei WP, Neto VF.

Source

Natural Products Department, National Institute for Amazon Research, Manaus, Brazil.

Abstract

Bites Bites of mosquitoes belonging to the genera Anopheles Meigen, Aedes Meigen, Culex L. and Haemagogus L. are a general nuisance and are responsible for the transmission of important tropical diseases such as malaria, hemorrhagic dengue and yellow fevers and filariasis (elephantiasis). Plants are traditional sources of mosquito repelling essential oils (EOs), glyceridic oils and repellent and synergistic chemicals. A Chemical Abstracts search on mosquito repellent inventions containing plant-derived EOs revealed 144 active patents mostly from Asia. Chinese, Japanese and Korean language patents and those of India (in English) accounted for roughly 3/4 of all patents. Since 1998 patents on EO-containing mosquito repellent inventions have almost doubled about every 4 years. In general, these patents describe repellent compositions for use in topical agents, cosmetic products, incense, fumigants, indoor and outdoor sprays, fibers, textiles among other applications. 67 EOs and 9 glyceridic oils were individually cited in at least 2 patents. Over 1/2 of all patents named just one EO. Citronella [Cymbopogon nardus (L.) Rendle, C.winterianus Jowitt ex Bor] and eucalyptus (Eucalyptus LʼHér. spp.) EOs were each cited in approximately 1/3 of all patents. Camphor [Cinnamomum camphora (L.) J. Presl], cinnamon (Cinnamomum zeylanicum Blume), clove [Syzygium aromaticum (L.) Merr. & L.M. Perry], geranium (Pelargonium graveolens LʼHér.), lavender (Lavandula angustifolia Mill.), lemon [Citrus × limon (L.) Osbeck], lemongrass [Cymbopogon citratus (DC.) Stapf] and peppermint (Mentha × piperita L.) EOs were each cited in > 10% of patents. Repellent chemicals present in EO compositions or added as pure “natural” ingredients such as geraniol, limonene, p-menthane-3,8-diol, nepetalactone and vanillin were described in approximately 40% of all patents. About 25% of EO-containing inventions included or were made to be used with synthetic insect control agents having mosquito repellent properties such as pyrethroids, N,N-diethyl-m-toluamide (DEET), (±)-p-menthane-3,8-diol (PMD) and dialkyl phthalates. Synergistic effects involving one or more EOs and synthetic and/or natural components were claimed in about 10% of all patents. Scientific literature sources provide evidence for the mosquito repellency of many of the EOs and individual chemical components found in EOs used in patented repellent inventions.© Georg Thieme Verlag KG Stuttgart · New York.

 

4. Asian Pac J Trop Biomed. 2011 Apr;1(2):85-8. doi: 10.1016/S2221-1691(11)60001-4.Bioefficacy of Mentha piperita essential oil against dengue fever mosquito Aedes aegypti L.Kumar S, Wahab N, Warikoo R.

Source

Department of Zoology, Acharya Narendra Dev College (University of Delhi), New Delhi-110019, India.

Abstract

OBJECTIVE:

To assess the larvicidal and repellent potential of the essential oil extracted from the leaves of peppermint plant, Mentha piperita (M. piperita) against the larval and adult stages of Aedes aegypti (Ae. Aegypti).

METHODS:

The larvicidal potential of peppermint oil was evaluated against early fourth instar larvae of Ae. aegypti using WHO protocol. The mortality counts were made after 24 and 48 h, and LC50 and LC90 values were calculated. The efficacy of peppermint oil as mosquito repellent was assessed using the human-bait technique. The measured area of one arm of a human volunteer was applied with the oil and the other arm was applied with ethanol. The mosquito bites on both the arms were recorded for 3 min after every 15 min. The experiment continued for 3 h and the percent protection was calculated.

RESULTS:

The essential oil extracted from M. piperita possessed excellent larvicidal efficiency against dengue vector. The bioassays showed an LC50 and LC90 value of 111.9 and 295.18 ppm, respectively after 24 h of exposure. The toxicity of the oil increased 11.8% when the larvae were exposed to the oil for 48 h. The remarkable repellent properties of M. piperita essential oil were established against adults Ae. aegypti. The application of oil resulted in 100% protection till 150 min. After next 30 min, only 1-2 bites were recorded as compared with 8-9 bites on the control arm.

CONCLUSIONS:

The peppermint essential oil is proved to be efficient larvicide and repellent against dengue vector. Further studies are needed to identify the possible role of oil as adulticide, oviposition deterrent and ovicidal agent. The isolation of active ingredient from the oil could help in formulating strategies for mosquito control.

KEYWORDS:

% protection, Adulticide, Aedes aegypti, Bioefficacy, Dengue, Essential oil, Larvicidal potential, Larvicide, Mentha piperita, Repellent

PMID:

23569733

[PubMed]

PMCID:

PMC3609176

5. J Med Entomol. 2006 Jul;43(4):731-6.

Repellency of oils of lemon eucalyptus, geranium, and lavender and the mosquito repellent MyggA natural to Ixodes ricinus (Acari: Ixodidae) in the laboratory and field.

Jaenson TG, Garboui S, Palsson K.

Source

Medical Entomology Unit, Department of Systematic Zoology, Evolutionary Biology Centre, Uppsala University, Norbyvägen 18d, SE-752 36 Uppsala, Sweden.

Abstract

MyggA Natural (Bioglan, Lund, Sweden) is a commercially available repellent against blood-feeding arthropods. It contains 30% of lemon-scented eucalyptus, Corymbia citriodora (Hook.) K. D. Hill & L. A. S. Johnson (Myrtaceae), oil with a minimum of 50% p-menthane-3,8-diol. MyggA Natural also contains small amounts of the essential oils of lavender, Lavandula angustifolia Mill. (Lamiaceae), and geranium, Pelargonium graveolens L’Her. (Geraniaceae). In laboratory bioassays, MyggA Natural and C. citriodora oil exhibited 100% repellency against host-seeking nymphs of Ixodes ricinus (L.) (Acari: Ixodidae). Lavender oil and geranium oil, when diluted to 1% in 1,2-propanediol, had weak repellent activities on I. ricinus nymphs, but when diluted to 30% in 1,2-propanediol had 100% repellencies. 1,2-Propanediol (100%) had no significant repellent activity in comparison with that of the control. In field tests in tick-infested areas in central Sweden, tick repellency of MyggA Natural and C. citriodora oil was tested by the blanket-dragging technique for 4 d during a 6-d period. The repellencies (74 and 85%, respectively) on day 1 are similar (89%) to that of blankets treated in a similar manner with 19% diethyl-methyl-benzamide, based on previous work. Repellencies declined significantly from day 1 to day 6 (74 to 45% for MyggA Natural; 85 to 42% for C. citriodora oil).

PMID:

16892632

[PubMed – indexed for MEDLINE]

6.Parasitol Res. 2006 Sep;99(4):473-7. Epub  2006 Apr 27.

Persistency of larvicidal effects of plant oil extracts under different storage conditions.

Amer A, Mehlhorn H.

Source

Omar Almukhtar University, P.O. Box 919, Elbieda, Libya. [email protected]

Abstract

The persistency of larvicidal effects of 13 oils (camphor, thyme, amyris, lemon, cedarwood, frankincense, dill, myrtle, juniper, black pepper, verbena, helichrysum, and sandalwood) was examined by storage of 50-ppm solutions under different conditions (open, closed, in the light, and in the dark) for 1 month after the preparation of the solutions. The stored solutions were tested against Aedes aegypti larvae for four times during the storage period. Some oils under some conditions stayed effective until the last test, while some solutions had lost their toxicity during a short time after preparation. Thus, the mode of storage is absolutely important for the larvicidal effects. The fresh preparations were always the best.

PMID:

16642385

[PubMed – indexed for MEDLINE]

7. J Egypt Soc Parasitol. 2000 Apr;30(1):101-15.

Larvicidal activity of Commiphora molmol against Culex pipiens and Aedes caspius larvae.Massoud AM, Labib IM.

Source

Department of Tropical Medicine, Faculty of Medicine, El-Azhar University, Cairo, Egypt.

Abstract

Myrrh (oleo-gum-resin) obtained from the stem of Commiphora molmol proved to have insecticidal activity against mosquito larvae. The oil extract of Myrrh possesses median lethal activity against 2nd, 3rd and 4th instar larvae of Culex pipiens at 0.016 x 10(2), 0.17 x 10(2) & 1.6 x 10(2) g/l respectively. While LC50 against 3rd instar larvae of Aedes caspius was 0.2 x 10(2) g/l. The oleo-resin extract showed toxicity against 2nd, 3rd, 4th instar larvae of C. pipiens recording the LC50 values of 0.06 x 10(2), 0.09 x 10(2) & 0.5 x 10(2) g/l respectively. While LC50 against 3rd instar larvae of A. caspius was 0.08 x 10(2) g/l. This plant extract has no marked toxic effect against the water bug Sphaerodema urinator (Dufor) and the water beetle Hydaticus leander (Rossi). Histological examinations of Myrrh treated mosquito larvae showed great pathological effect on their fat, muscles, gut and nervous tissues.

PMID:

10786023

[PubMed – indexed for MEDLINE]


Pain USA, PTSD with Military soldiers

Posted on: July 12th, 2013 |

 

 

On my Martial arts website, I wrote an article about research on joints.  (See Professor Vandry’s View Again the Racehorse theory for Joints! Collagen 1, 2, and 3, Vitamins and Minerals for the joints, Serrazyme Nattokinese (fibrinogen breakup), Lumen 90, and of course St. Jude’s Miracle Oil®!)1

From the article above, the SJMO refers to medical journals for limited references on how these oils work.  Regarding the title of this article, we refer to medical journals on each of our 9 oils in St. Jude’s Miracle Oil®2

Wintergreen acts as an anti-inflammatory agent (1-4).  The medicinal properties of peppermint oil are analgesic, anti-septic, anti-inflammatory, and antimicrobial, among others (5).  Lavender has anti-inflammatory and analgesic properties (6), and pain relief assessment (7).  Eucalyptus Blue has anti-inflammatory and analgesic properties (8), Clove bud has anti-infectious properties include: anti-viral, anti-bacterial, anti-fungal effects (9-10).  Geranium has shown temporary relief of neuralgia pain (11).  Clary Sage in pain relief on outpatients with primary dysmenorrhea (12).  Frankincense was used for symptomatic knee osteoarthritis. (13) Myrrh oil has anti-inflammatory and analgesic activity (14). 

As referenced on another website, Essential oils do not require FDA approval.  However, manufacturers are not allowed to claim that they prevent or treat illness. We do not make claims such as those, but oils in our product have been used separately in clinical trials in medical journals I have researched.  Our goal is to explore clinical trials with our oil regarding the above results from medical journals.  When we research inflammation, or infection, viral and others, many wonder who does this effect?  How many people in society can use this?  This is in my opinion a huge wakeup to developing alternative means to our standard system that has criticism.

Military veteran’s service connected disabilities…pain, pain, pain!

bva7

(Added photo: William Vandry lecturing research on pain, nutrition, diseases of legal blindness to VFW/BVA San Antonio 2014)

Nationally, according to the federal Veterans Benefits Administration, musculoskeletal conditions were the No. 1 service-connected disability for veterans every year from 2007 to 2011.

Overview of Pain in the United States and the Military Health System on pain statistics:

This basically translates into Pain is the most frequent reason patients seek physician care in the United States, and more than 50 million Americans suffer from chronic pain.  The annual cost of chronic pain in the U.S. is estimated at $100 billion, including health care expenses, lost income, and lost productivity.  Back pain alone is the leading cause of disability in Americans under 45 years of age. The failure to adequately address pain in the health care system continues to result in unnecessary suffering, exacerbation of other medical conditions, and huge financial and personnel costs. 

According to the American Academy of Pain Medicine, “pain medicine” is a relatively new medical specialty that is evolving along with its place in the medical hierarchy.  Although there are many treatment modalities for pain management, one of the major components for the treatment of pain continues to be the use of Over-The-Counter and prescription medications.

The use of medications is appropriate, required, and often an effective way to treat pain. However, the possible overreliance on medications to treat pain has other unintended consequences, such as the increased prevalence of prescription medication abuse and diversion throughout the United States.  According to the Office of National Drug Control Policy, prescription opioid analgesics are the most commonly abused prescription drugs in the U.S., with the highest rate of abuse occurring among those ages 18-25.

For patients interested in treatments other than, or in addition to, medication, Complementary Alternative Medicine (CAM) is a popular option.

Though CAM is increasing in popularity among patients, this popularity has yet to result in a parallel increase in acceptance and use within traditional medicine.

There is a wide range of these therapies and treatments, such as acupuncture and yoga therapy, that have proven valuable in reducing an overreliance on use of medications to treat pain.  Many of the Military Health System’s (MHS) challenges with pain management are very similar to those faced by other medical systems, but the MHS also faces some unique issues because of its distinctive mission, structure and patient population.

The Pain Management Task Force developed 109 recommendations that lead to a comprehensive pain management strategy that is holistic, multidisciplinary, and multimodal in its approach, utilizes state of the art/science modalities and technologies, and provides optimal quality of life for Soldiers and other patients with acute and chronic pain. 

The recommendations rely heavily on an education and communication plan that crosses DoD and VHA medical staff and patients. The Task Force also placed an emphasis on linking to existing Service and MHS initiatives (e.g. Patient Centered Medical Home, Comprehensive Soldier Fitness) that support the pain management strategy. The requirement to synchronize both effort and approach to pain management across the MHS and VHA is an essentialfirst step in combating the variability that plagues pain management across the MHS. This requirement was the driving force behind many of the other TF recommendations.

 Pain Management Task Force Final Report:

• One study reported 48% of veterans experienced pain regularly and expressed concern over their pain. Use of outpatient medical services in these veterans was significantly higher than those that did not report chronic pain.1

• A separate study of veterans found that the most common chronic pain conditions were joint pain, back pain, headaches, limb pain, and abdominal pain.  Women had a significantly higher prevalence of headache, abdominal, and limb pain than men, and men had a significantly higher prevalence of back pain and joint pain than women. Chronic chest pain was similar in both samples. Among the  women, 82.5% met the sample criteria for a single pain site, and 17.5% had multiple pain sites. In comparison, 86.7% of men met the sample criteria for a single pain site, and 13.3% had multiple pain sites.2

• In recent years, the Afghan and Iraq Wars have increased the prevalence of migraines and headaches in veterans returning to theUnited States.

In one study of 3,621U.S.soldiers screened within 90 days of returning from a one-year combat tour in Iraq, soldiers were shown to have two to four times the incidence rate of migraine as compared to the general population.3

•   Chronic pain and PTSD are often found together (co-morbid). In one study of veterans with PTSD, 66% had chronic pain diagnoses at pretreatment. Patients with more pain before treatment reported reductions in pain over the course of PTSD treatment and in the four months following treatment.4

•  One study found that Gulf War deployment was associated with higher prevalence of Chronic Widespread Pain (CWP) than deployment elsewhere. Both deployed and non-deployed veterans with CWP reported more health care utilization and co-morbidities and lower health-related quality of life scores than veterans without CWP. Deployed veterans were more likely to have CWP than non-deployed veterans, and CWP was associated with poor health outcomes.5

•   Among the Gulf War veterans evaluated in a separate study, family history, pre-deployment symptoms, and the level of perceived stress during the war were associated with subsequent development of CWP.6

•   An estimated 17.6% of veterans with Gulf War syndrome have also shown an association with fibromyalgia.7

(NOTE:  If you are a vet reading this or someone who has fibromyalgia, refer to the article on my other website on joints and the MD research on nattokinese)

• The most common reasons for medical evacuation of military personnel from war zones in Iraq and Afghanistan in recent years have been fractures, tendonitis and other musculoskeletal and connective tissue disorders, not combat injuries, according to results of a Johns Hopkins study.8

•   Military personnel evacuated out of Iraq and Afghanistan because of back pain are unlikely to return to the line of duty regardless of the treatment they receive, according to research led by a Johns Hopkins pain management specialist.  Researchers found that just 13% of service members who left their units with back pain as their primary diagnosis eventually returned to duty in the field.

Women, officers, those deployed in Afghanistan and those with previous back pain had better outcomes, but only marginally. Aside from combat injuries sustained during battle, the return-to-duty rate for spinal pain and other musculoskeletal disorders is lower than for any other disease or non-combat injury category except for psychiatric illness, the researchers said.9

• Research has found that being female, enlisted rank groups, service in the Army, Navy, or Air Force, age greater than 40 years, and a marital status of married were all risk factors for low back pain among active-duty military. Each service, when compared with the Marines as the referent category, had a significantly increased incidence rate ratio of low back pain:10

– Army: 2.19

– Navy: 1.02

– Air Force: 1.54

• One study of racial differences among active-duty military with low-back pain.

• A survey of VA primary care providers (PCPs) found:19 – 77% of respondents identified pain control among the top three treatment priorities.

– primary care physicians who did not choose pain control were more likely to indicate that chronic pain patients should see a specialist (54% vs. 35%)

– of the respondents, 86% reported psychology or mental health clinics were available at their clinic site; 71%, physical therapy; and 20%, multidisciplinary pain clinics most PCPs (74%) were satisfied with the quality of care they provide for patients with chronic pain but only 30% were satisfied with access to pain specialty services

• In the first study to look at sex-specific pain prevalence in Operation Enduring Freedom/ Operation Iraqi Freedom (OEF/OIF) Veterans, researchers from the VA Connecticut Healthcare System and the Yale University School of Medicine found women veterans had a lower prevalence of pain than male counterparts returning from the conflicts.11

– Results indicate that of those veterans evaluated for pain, 43.3% reported any pain, 63.2% of those with pain reported moderate-severe pain, and over 20% of those with pain scores recorded over three months’ time reported persistent pain.

– According to the study, female veterans were less likely to report any pain (38.1% vs. 44.0%). In veterans with any pain, researchers found female veterans were 6% more likely to report moderate-severe pain (68.0% vs. 62.6%) and less likely to report having persistent pain (18.0% vs. 21.2%) than male colleagues.12

• One study of veterans with chronic non-cancer pain found that more than 80% reported previously trying CAM, and almost all reported a willingness to try one or more of the four CAM modalities being studied (massage, acupuncture, chiropractic, herbal medicine).

– Veterans in the study who had already tried CAM treatments differed little from veterans who had not, suggesting that many veterans experiencing chronic pain may be interested in CAM treatment options for chronic pain. The results of this study support the VA’s increasing movement toward offering CAM modalities as treatment options for pain.13

• Based on a large, nationally representative sample, a recent publication reported that military veterans were twice as likely to commit suicide as nonveterans.

Chronic pain and depression – two conditions not uncommon in VA medical settings – are leading contributing factors in deaths by suicide.

A systematic literature review of pain and suicide, suicide attempts and thoughts of suicide revealed that patients with chronic pain had a 2-fold risk of death by suicide, a 14% prevalence of suicide attempts (compared with 5% without chronic pain), and a 20% prevalence of suicide ideation.

 Solutions?

In researching pain, I have found injuries along with inflammation seems to be the main problem.  In other words, when we develop an injury, inflammation is consistent, and our needs for NSAIDS and other pain medications are the primary source of relief.  What seems to be a lack of knowledge is handling pain in society, and especially for our military.  I found that over the recent years, the military has looked at alternative pain therapy, and one  shows the  new approach to pain management at Dwight D. Eisenhower Army Medical Center is setting the tone for the rest of the Army:

“The recently launched interdisciplinary pain center focuses on replacing pain medication with alternative remedies such as acupuncture, along with teaching soldiers coping mechanisms for pain. It’s an important resource in an active duty force where muscular skeletal issues make up about 80 percent of medical board evaluations, said Maj. Jeffrey Tiede, the chairman of Eisenhower’s Department of Pain Management.”

Issues with essential oil

I am aware of many critical opinions on essential oils, but there are two issues:

1.  There are those who are excited about selling oils or health products, supplements, etc. and run into the same problems as many other health products, the ‘cure-all’ claims, or a claim that has no evidence, whether scientific or anecdotal. 

2. I have read opinions on skeptical websites with statements such as: “Why doesn’t Harvard fund research?”, and the implications are a misunderstood assessment or theory that there is no evidence is really a lack of information. 

We have references on this website to many medical journals we researched and found on essential oils, particularly the oils in our product.  There are benefits to essential oils that can be argued on a clinical level, although there definitely is a thirst for more thoroughly examined and funded research.  For example, medical journals generally show a very positive view on oils:

Psychological Response to Treatment

“Psychological responses to treatment were assessed as changes in anxiety and depression according to the STAI and SDS results.  State anxiety scores from the STAI were significantly reduced after both aromatherapy massage and control massage compared with the baseline obtained before the massage.”5

I feel the more important point would be a desire to fund more research instead of criticizing a subject without evidence.  Here is a  great article on PTSD and essential oils tackling this argument on PTSD:

Post-traumatic stress –can essential oils help?

Concerned that essential oils are often recommended for post-traumatic stress disorder with little supporting evidence, Susan Rands carried out a systematic literature review.

Conclusion:

“The results of this systematic review indicate that of the original 45 essential oils that were recommended for treating or managing PTSD only four – lavender, lemon, roman chamomile and ylang ylang – may be effective in treating some of the symptoms of PTSD such as anxiety, depression, insomnia, re-experiencing and anger. Currently, there is not sufficient evidence arising from blinded RCTs to support the use of the remaining 41 oils.” 

(My insert here.  On the website I saw a very thorough research study on the limited essential oils study.)

The potential for using essential oils in the treatment of PTSD needs to be researched further since their value may lie in providing safe alternatives or complements to anxiolytic and antidepressant medications in order to improve PTSD sufferers’ sense of well-being.  Of the 525 papers found in the first search only two investigated the use of essential oils in the treatment of PTSD. 

One looked at the use of essential oils in conjunction with hypnosis, but it was the hypnosis that was the focus of the study (Abramovitz, 2009).

The other (for which only an abstract was found) discussed aromatherapy and physiotherapy as precursors to counselling (Kinchin, 1997). 

The second stage of the search located 1228 peer reviewed papers of which 28 complied with the inclusion/exclusion criteria. The third stage of the search located 959 papers of which 32 were selected for potential inclusion in the systematic review.  Of the 60 papers with potential for inclusion, 25 could only be located as abstracts, four were excluded because they were animal rather than human studies, and one paper was excluded because it studied the effect of ingestion.

The remaining 30 papers were scrutinised for scientific rigour of methodology in accordance with the Oxford Centre for Evidence-based Medicine Levels of Evidence criteria.6

Evidence?  Response to the “Where are the Harvard studies?”

I believe the issues above show a very low effort to give scientific evidence on essential oils is directed to the point of the study.  Going back to just pain (since this is the subject regarding people in general and the military) , referring to the oils in our product, we need to reiterate some scientific research on pain and oils.  Reference above to our oils are evidence, but specifically and briefly here are studies on some of our essential oils for pain:

Lavender has  pain relief assessment. 

Geranium has shown temporary relief of neuralgia pain. 

Clary Sage in pain relief on outpatients with primary dysmenorrhea.

Now going back to inflammation, essential oils in our product have anti inflammatory effects, which are keys to pain.  Athletes need ice, then the RICE method (rest, ice, elevation, compression) but what does it do?  It reduces inflammation, circulates blood, lowers swelling, etc.. You cannot recover from an injury until you reduce the inflammation.  This demands more scientific study on the effects on inflammation and pain relief. 

Are there more specific references to trials with essential oils and pain?  YES!

1. Aromatherapy has major effects on decreasing pain and depression levels, and can be a useful nursing intervention for arthritis patients.  The essential oils used were lavender, marjoram, eucalyptus, rosemary, and peppermint

Collegeof Nursing, The Catholic University of Korea, Korea, Taehan Kanho Hakhoe Chi. 2005 Feb;35(1):186-94. 

(The effects of aromatherapy on pain, depression, and life satisfaction of arthritis patients)

2. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.  Essential oils blended with lavender (Lavandula officinalis), clary sage (Salvia sclarea) and marjoram (Origanum majorana) 

Department of Applied Cosmetology, Hungkuang University, Taichung, Taiwan.  J Obstet Gynaecol Res. 2012 May;38(5):817-22. doi: 10.1111/j.1447-0756.2011.01802.x. Epub  2012 Mar 22

3. Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations for the relief of acute and inflammatory pain in sports injuries, arthritis an Pain

Department of Pharmacology, Yale University School of Medicine, 333 Cedar St., New Haven,CT06520.                                                                                                                                             2013 Jun 29. pii: S0304-3959(13)00364-3. doi: 10.1016/j.pain.2013.06d other painful conditions

4.  The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata (Syzigium aromaticum L. Myrtaceae): a short review  (The essential oil extracted from the dried flower buds of clove, Eugenia caryophyllata L. Merr. & Perry (Myrtaceae), is used as a topical application to relieve pain and to promote healing)  Laboratoire d’Analyses, Traitement et Valorisation des Polluants de l’Environnement et des Produits, Faculté de Pharmacie, rue Avicenne 5000 Monastir, Tunisie. Phytother Res. 2007 Jun;21(6):501-6.

5.  Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer.  (Aroma hand massage had a positive effect on pain and depression in hospice patients with terminal cancer.) 

Department of Nursing, KeimyungUniversity, Jung-gu, Daegu, Korea.  Taehan Kanho Hakhoe Chi. 2008 Aug;38(4):493-502.

I found some disturbing numbers on PTSD and suffering of our military soldiers:

Up to 37% of the over two million service members who have deployed to Iraq or Afghanistan are struggling with serious mental health problems including post-traumatic stress disorder (PTSD), major depression, and traumatic brain injury.[1]

These mental health conditions result in debilitating pain and suffering and are associated with additional problems including addiction, difficulties maintaining work, and homelessness.[2]

These mental health issues can lead to tragic consequences, as illustrated by increasing military suicide rates.

Active duty suicides reached epidemic levels in 2010 with one active duty service member committing suicide every 36 hours.

Our Veterans are killing themselves at twice the rate of other Americans.[3]-[4]

Fortunately, there are effective treatments for these mental health problems and a great number of clinicians dedicated to helping our nations heroes.  Unfortunately, even when provided with the best evidence-based treatments, non-response rates can be as high as 50%.[7]

In addition, access to these treatments may be obstructed by an array of institutional and diagnosis-related barriers.

 I literally could research on and on, but the point is a large demand for more research.  Chronic pain with the general public and especially our military veterans relate with inflammation, insomnia, stress, nutrition and other areas.  We need to develop funding for more projects that involve our military with PTSD, pain, inflammation, and even the secondary effects such as anxiety, depression and hopefully to regain their peace of mind in society.  God bless our military soldiers.  I pray for your speedy recovery.

bva5

Photo: Blind Veterans San Antonio President Wally Guerra and William Vandry

William Vandry (Co-inventor SJMO product, researcher)

References

 

1. http://www.William Vandry.com/2013/04/28/professor-vandrys-view-again-the-racehorse-theory-for-joints-collagen-1-2-and-3-vitamins-and-minerals-for-the-joints-serrazyme-nattokinese-fibrinogen-breakup-lumen-90-and-of-course/

2. 9 essentil oils of SJMO

 

1. Methyl salicylate 2-O-β-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes.Lan X, Liu R, Sun L, Zhang T, Du G.J Neuroinflammation. 2011 Aug 11;8:98. doi: 10.1186/1742-2094-8-98.

2. A novel naturally occurring salicylic acid analogue acts as an anti-inflammatory agent by inhibiting nuclear factor-kappaB activity in RAW264.7 macrophages. Zhang T, Sun L, Liu R, Zhang D, Lan X, Huang C, Xin W, Wang C, Zhang D, Du G.Mol Pharm. 2012 Mar 5;9(3):671-7. doi: 10.1021/mp2003779. Epub 2012 Feb 15.

3. Anti-inflammatory activity of methyl salicylate glycosides isolated from Gaultheria yunnanensis (Franch.) Rehder.Zhang D, Liu R, Sun L, Huang C, Wang C, Zhang DM, Zhang TT, Du GH.  Molecules. 2011 May 9;16(5):3875-84. doi: 10.3390/molecules16053875

4. Evaluation of the new anti-inflammatory compound ethyl salicylate 2-O-β-d-glucoside and its possible mechanism of action.  Xin W, Huang C, Zhang X, Zhang G, Ma X, Sun L, Wang C, Zhang D, Zhang T, Du G.Int Immunopharmacol. 2012 Dec 4;15(2):303-308. doi:10.1016/j.intimp.2012.11.014.

5. Mullally BH, James JA,CoulterWA,LindenGJ. The efficacy of a herbal-based toothpaste on the control of plaque and gingivitis. J Clin Periodontol. 1995;22(9):686–9.

6. Hajhashemi, V., Ghannadi, A., & Sharif, B. (2003). Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of lavandula angustifolia mill. Journal of Ethnopharmacology, 89(1), 67-71.(Lavender)

7. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.  Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC.  SourceDepartment of Applied Cosmetology,HungkuangUniversity,Taichung,Taiwan

8. Phytochemical composition of Cymbopogon citratus and Eucalyptus citriodora essential oils and their anti-inflammatory and analgesic properties on Wistar rats.  Gbenou JD, Ahounou JF, Akakpo HB, Laleye A, Yayi E, Gbaguidi F, Baba-Moussa L, Darboux R, Dansou P, Moudachirou M, Kotchoni SO.  SourceLaboratoire de Pharmacognosie et des Huiles Essentielles, Faculté des Sciences de la Santé, Faculté des Sciences et Techniques, Université d’Abomey Calavi, 01 BP 918,Cotonou,Benin.

9. Antifungal activity of the clove essential oil from aromaticum on Candida, Aspergillus and dermatophyte species Euge´ nia Pinto,1 Luı´s Vale-Silva,1 Carlos Cavaleiro2 and Lı´gia Salgueiro2

10. Curr Med Chem. 2003 May;10(10):813-29.Antibacterial and antifungal properties of essential oils.  Kalemba D, Kunicka A.SourceInstitute of General Food Chemistry, TechnicalUniversity of Lodz,Poland.

11. 20Greenway, f, Frome & Engels, T. (2003). Temporary relief of postherpetic neuralgia pain with topical geranium oil. American J of Medicine, 115, 586-587.

12. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.  Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC.  SourceDepartment of Applied Cosmetology, HungkuangUniversity, Taichung, Taiwan.

13. Rheumatology (Oxford). 2013 Jan 30. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.  Source Center for Rheumatic Diseases, Pune, School of Biomedical Sciences, Symbiosis International University, Pune, BJ Medical College, Pune, Department of Rheumatology, Nizam Institute of Medical Sciences, Hyderabad, Department of Medicine, All India Institute of Medical Sciences, Delhi, Interactive Research School for Health Affairs, Bharati Vidyapeeth Deemed University, Pune, SPARC Institute, Mumbai, Department of Medicine, KEM Hospital, Mumbai and Symbiosis International University, Pune, India

14. Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha.  Source:JiangsuKey Laboratory for TCM Formulae Research,NanjingUniversityof   Chinese Medicine,Nanjing210046, PR China.

3. References:

1. Kerns R, Otis J, Rosenburg R, Reid C. “Veterans’ reports of pain and associations with ratings of health, health-risk behaviors, affective distress, and use of the healthcare system.” J Rehabil Res Dev. 2003 Sept-Oct;40(5):371–80.

2. Kaur S, Stechuchak K et al. “Gender differences in health care utilization among veterans with chronic pain.” J Gen Intern Med. 2007 Feb;22(2):228–233.

3. Nati

4. Shipherd JC, Keyes M, Jovanovic T, Ready DJ, Baltzell D, Worley V, Gordon-Brown V, Hayslett C, Duncan E. “Veterans seeking treatment for posttraumatic stress disorder: what about comorbid chronic pain?” J Rehabil Res Dev. 2007;44(2):153-66.

5. Forman-Hoffman VL, Peloso PM, Black DW, Woolson RF, Letuchy EM, Doebbeling BN. “Chronic widespread pain in veterans of the first Gulf War: impact of deployment status and associated health effects.” J Pain. 2007 Dec;8(12):954-61.

6. Ang DC, Peloso PM, Woolson RF, Kroenke K, Doebbeling BN. “Predictors of incident chronic widespread pain among veterans following the first Gulf War.” Clin J Pain. 2006 Jul-Aug;22(6):554-63.

7. Yunus M, “The Prevalence of Fibromyalgia in Other Chronic Pain Conditions.” Pain Res and Treatment. 2012:1-8.

8. Cohen S, Brown C, Kurihara C, Plunkett A, Nguyen C, Strassels S. “Diagnoses and factors associated with medical evacuation and return to duty for service members participating in Operation Iraqi Freedom or Operation Enduring Freedom: a prospective cohort study.” Lancet. 2010 Jan;375:301-309.

9. Aldington D. “Back pain: the silent military threat.” Arch Internal Med. 2009 Nov;169(20):1923-24.

10. Knox J, Orchowski J, Scher DL, Owens BD, Burks R, BelmontPJ. “The incidence of low back pain in active duty United States military service members.” Spine. 2011 Aug 15;36(18):1492-500.onal Headache Foundation. War Veterans Health Resource Initiative. http://www.headaches.org/warveterans/index.html. Accessed June 27, 2012.

11. Kaur S, Stec

12. Haskell S, Brandt C, Krebs E, Skanderson M, Kerns R, Goulet J. “Pain among veterans of Operations Enduring Freedom and Iraqi Freedom: do women and men differ?” Pain Med. 2009 Oct;10(7):1167.

13. Denneson L, Corson K, Dobscha S. “Complementary and alternative medicine use among veterans with chronic non cancer pain.” J Rehab Res Dev. 2011;48(9)1119:1128.huchak K et al. “Gender differences in health care utilization among veterans with chronic pain.” J Gen Intern Med. 2007 Feb;22(2):228–233.

4. (The role of pain management in recovery following trauma and orthopaedic surgery.  J Am Acad Orthop Surg. 2012;20 Suppl 1:S35-8. doi: 10.5435/JAAOS-20-08-S35.  Walter Reed Army Medical Center, Washington, DC, USA.)

5. Immunological and Psychological Benefits of Aromatherapy Massage  (Evid Based Complement Alternat Med. 2005 June; 2(2): 179–184. )

6. References:

Abramovitz, E.G. and Lichtenberg, P. (2009) Hypnotherapeutic olfactory conditioning (HOC): case studies of needle phobia, panic disorder and combat-induced PTSD. International Journal of Clinical and Experimental Hypnosis. 57 (2) pp.184-197.

Anon, (1998) Practice Parameters for the Assessment and Treatment of Children and Adolescents With Post Traumatic Stress Disorder. Journal of the American Academy of Child & Adolescent Psychiatry  37 (10) pp.4S-26S.  Braden, R., Reichow, S. and Halm, M. A. (2009) The Use of the Essential Oil Lavandin to Reduce Preoperative Anxiety in Surgical Patients. Journal of PeriAnesthesia Nursing. 26

(6) pp.348-355. Dileo, J. F., Brewer, W. J., Hopwood, M., Anderson, V. and Creamer, M. (2008) Olfactory

7. PTSD and suffering of our military soldiers References:

1] Seal KH, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR. Trends and Risk Factors for Mental Health Diagnoses Among Iraq and Afghanistan Veterans Using Department of Veterans Affairs Health Care, 2002-2008. Am J Public Health. September 1, 2009 2009;99(9):1651-1658.

[2]Karney BR, Ramchand R, Osilla KC, Calderone LB, Burns RM. Predicting the Immediate and Long-Term Consequences of Post-Traumatic Stress Disorder, Depression, and Traumatic Brain Injury in Veterans of Operation Enduring Freedom and Operation Iraqi Freedom. In: Tanielian TL, Jaycox LH, eds. Invisible Wounds of War: Psychological and cognitive injures, their consequences, and services to assist recovery. Santa Monica, CA: Rand Corporation; 2008.

[3] McFarland BH, Kaplan MS, Huguet N. Datapoints: Self-Inflicted Deaths Among Women With U.S. Military Service: A Hidden Epidemic? Psychiatr Serv. December 1, 2010;61(12):1177.

[4] Kaplan MS, Huguet N, McFarland BH, Newsom JT. Suicide Among Male Veterans: A Prospective Population-based Study. Journal of Epidemiology and Community Health. July 1, 2007 2007;61(7):619-624.

[7] Schottenbauer MA, Glass CR, Arnkoff DB, Tendick V, Gray SH. Nonresponse and Dropout Rates in Outcome Studies on PTSD: Review and Methodological Considerations. Psychiatry:recoveries, all of you. Interpersonal & Biological Processes. 2008;71(2):134-168.